Reduction of Matrix Metallopeptidase 13 and Promotion of Chondrogenesis by Zeel T in Primary Human Osteoarthritic Chondrocytes

• Principais autores: Christelle Sanchez (Autor), Kathrin Hemmer (Autor), Natascha Krömmelbein (Autor), Bernd Seilheimer (Autor), Jean-Emile Dubuc (Autor), Christophe Antoine (Autor), Yves Henrotin (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objectives: Zeel T (Ze14) is a multicomponent medicinal product. Initial preclinical data suggested a preventive effect on cartilage degradation. Clinical observational studies demonstrated that Ze14 reduced symptoms of osteoarthritis (OA), including stiffness and pain. This study aimed to explore t...