Accelerating vaccine trial conduct in a pandemic with a hot spot‐based inclusion strategy using trial and epidemic simulation

• Κύριοι συγγραφείς: Johan L. van derPlas (Συγγραφέας), Michiel J. vanEsdonk (Συγγραφέας), Ingrid M. C. Kamerling (Συγγραφέας), Adam F. Cohen (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Wiley, 2021-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Clinical development of vaccines in a pandemic situation should be rigorous but expedited to tackle the pandemic threat as fast as possible. We explored the effects of a novel vaccine trial strategy that actively identifies and enrolls subjects in local areas with high infection rates. In a...