Prediction of pediatric dose of tirzepatide from the reference adult dose using physiologically based pharmacokinetic modelling

Tirzepatide is an emerging hypoglycemic agent that has been increasing used in adults, yet its pharmacokinetic (PK) behavior and dosing regimen in pediatric population remain unclear. This study aimed to employ the physiologically based pharmacokinetic (PBPK) model to predict changes of tirzepatide...

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Váldodahkkit: Ruifang Guan (Dahkki), Xuening Li (Dahkki), Guo Ma (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: Frontiers Media S.A., 2023-11-01T00:00:00Z.
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