Low expression of E-Cadherin and Cdh1 variants associated with diffuse gastric cancer

• Main Authors: Azaria García-Ruvalcaba (Author), Katia C. Vázquez-Ibarra (Author), María T. Magaña-Torres (Author), Lourdes del C. Rizo de la Torre (Author), Lennon Meléndez-Aranda (Author), Gabriela López-Armas (Author), José A. Cruz-Ramos (Author), Jorge Peregrina-Sandoval (Author), Esther Espinoza-Jiménez (Author), María E. Rosales-Gradilla (Author), Josefina Y. Sánchez-López (Author)
• Format: Book
• Published: Permanyer, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Reduced or null expression of E-cadherin protein is a frequent cause of diffuse gastric cancer (DGC). More than 50% of patients with DGC present somatic variants in CDH1 gene. Objectives: The objectives of this study were to study E-cadherin expression and identify variants in the CDH1 g...