Period 2 Regulates CYP2B10 Expression and Activity in Mouse Liver

• Main Authors: MengLin Chen (Author), Min Chen (Author), Danyi Lu (Author), Yi Wang (Author), Li Zhang (Author), Zhigang Wang (Author), Baojian Wu (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

CYP2B10 is responsible for metabolism and detoxification of many clinical drugs. Here, we aimed to investigate a potential role of Period 2 (PER2) in regulating expression of hepatic CYP2B10. Regulatory effects of PER2 on hepatic expression of CYP2B10 and other enzymes were determined using Per2-def...