Biomarker recommendation for PD‐1/PD‐L1 immunotherapy development in pediatric cancer based on digital image analysis of PD‐L1 and immune cells

• Main Authors: Manuel A Silva (Author), Nicolas Triltsch (Author), Simon Leis (Author), Ivan Kanchev (Author), Tze Heng Tan (Author), Benjamine Van Peel (Author), Marian Van Kerckhoven (Author), Vanessa Deschoolmeester (Author), Johannes Zimmermann (Author)
• Format: Book
• Published: Wiley, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Anti‐PD‐1/PD‐L1 immunotherapy could offer an alternative to traditional chemo‐ and/or radiotherapy to treat pediatric cancer patients. To unveil the potential benefit of this new therapeutic approach, the prevalence of PD‐L1 and other relevant immune markers using quantitative digital image...