Safety and immunogenicity of a recombinant Staphylococcus aureus α-toxoid and a recombinant Panton-Valentine leukocidin subunit, in healthy adults

• Main Authors: Michael L. Landrum (Author), Tahaniyat Lalani (Author), Minoo Niknian (Author), Jason D. Maguire (Author), Duane R. Hospenthal (Author), Ali Fattom (Author), Kimberly Taylor (Author), Jamie Fraser (Author), Kenneth Wilkins (Author), Michael W. Ellis (Author), Paul D. Kessler (Author), Rafaat E. F. Fahim (Author), David R. Tribble (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We conducted a randomized, double-blind, placebo-controlled dose-escalation study in healthy adults to evaluate the safety and immunogenicity of recombinant Staphylococcus aureus candidate vaccine antigens, recombinant α-toxoid (rAT) and a sub-unit of Panton-Valentine leukocidin (rLukS-PV). 176 subj...