Pharmacokinetic herb-drug interactions between Aidi injection and doxorubicin in rats with diethylnitrosamine-induced hepatocellular carcinoma

• Main Authors: Yuan Lu (Author), Jie Pan (Author), Xiaoqing Zhu (Author), Shuai Zhang (Author), Chunhua Liu (Author), Jia Sun (Author), Yueting Li (Author), Siying Chen (Author), Jing Huang (Author), Chuang Cao (Author), Yonglin Wang (Author), Yongjun Li (Author), Ting Liu (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aidi Injection (ADI), a Chinese herbal preparation with anti-cancer activity, is used for the treatment of hepatocellular carcinoma (HCC). Several clinical studies have shown that co-administration of ADI with doxorubicin (DOX) is associated with reduced toxicity of chemotherapy,...