Lung EC-SOD Overexpression Prevents Hypoxia-Induced Platelet Activation and Lung Platelet Accumulation

• Main Authors: Daniel Colon Hidalgo (Author), Mariah Jordan (Author), Janelle N. Posey (Author), Samuel D. Burciaga (Author), Thi-Tina N. Nguyen (Author), Christina Sul (Author), Caitlin V. Lewis (Author), Cassidy Delaney (Author), Eva S. Nozik (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary hypertension (PH) is a progressive disease marked by pulmonary vascular remodeling and right ventricular failure. Inflammation and oxidative stress are critical in PH pathogenesis, with early pulmonary vascular inflammation preceding vascular remodeling. Extracellular superoxide dismutase...