Nitric Oxide Inhibits Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase Expression and Its Own Production Through the cGMP Signaling Pathway in Murine Microglia BV-2 Cells

The present study examined the effect of the nitric oxide (NO) donor NOC18 on lipopolysaccharide (LPS)-induced NO production to investigate a regulation mechanism of NO production by microglial cells. LPS increased the levels of NO and inducible NO synthase (iNOS) protein in BV-2 murine microglial c...

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Main Authors: Yasuhiro Yoshioka (Author), Nobuo Takeda (Author), Akiko Yamamuro (Author), Atsushi Kasai (Author), Sadaaki Maeda (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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