A Japanese herbal medicine attenuates anxiety-like behavior through GABAA receptor and brain-derived neurotrophic factor expression in a rat model of premenstrual syndrome

• Main Authors: Hikari Iba (Author), Takuya Watanabe (Author), Saori Motomura (Author), Kyoka Harada (Author), Haruka Uesugi (Author), Takenori Shibahara (Author), Kaori Kubota (Author), Shutaro Katsurabayashi (Author), Katsunori Iwasaki (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inochinohaha White (IHW) is a Japanese herbal medicine for treating women with anxiety associated with premenstrual syndrome (PMS). In this study, we examined the effects of IHW on anxiety-like behavior in rats undergoing progesterone withdrawal (PWD), a model for PMS. Female rats were injected dail...