Conditional gene targeting using UCP1-Cre mice directly targets the central nervous system beyond thermogenic adipose tissues

• Main Authors: Kristin E. Claflin (Author), Kyle H. Flippo (Author), Andrew I. Sullivan (Author), Meghan C. Naber (Author), Bolu Zhou (Author), Tate J. Neff (Author), Sharon O. Jensen-Cody (Author), Matthew J. Potthoff (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Uncoupling protein 1 (UCP1) is a mitochondrial protein critical for adaptive thermogenesis in adipose tissues, and it is typically believed to be restricted to thermogenic adipose tissues. UCP1-Cre transgenic mice are utilized in numerous studies to provide "brown adipose-specific&qu...