An S-Nitrosylated Hemoglobin Derivative Protects the Rat Hippocampus From Ischemia-Induced Long-Term Potentiation Impairment With a Time Window

• Main Authors: Hiroshi Otani (Author), Subrina Jesmin (Author), Hiroko Togashi (Author), Ichiro Sakuma (Author), Kunihiko Nakai (Author), Hiroshi Satoh (Author), Mitsuhiro Yoshioka (Author), Akira Kitabatake (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Evidence suggests that S-nitrosylation is a biological process involved in cerebral ischemia. The aim of the present study was to elucidate the effects of S-nitrosylated (SNO) polyethylene glycol-conjugated (PEG) hemoglobin (Hb) developed as an artificial oxygen carrier, which can absorb free NO and...