Reservoir-Style Polymeric Drug Delivery Systems: Empirical and Predictive Models for Implant Design

• Main Authors: Linying Li (Author), Chanhwa Lee (Author), Daniela F. Cruz (Author), Sai Archana Krovi (Author), Michael G. Hudgens (Author), Mackenzie L. Cottrell (Author), Leah M. Johnson (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Controlled drug delivery systems can provide sustained release profiles, favorable pharmacokinetics, and improved patient adherence. Here, a reservoir-style implant comprising a biodegradable polymer, poly(ε-caprolactone) (PCL), was developed to deliver drugs subcutaneously. This work addresses a ke...