Clinical implementation of plasma cell-free circulating tumor DNA quantification by digital droplet PCR for the monitoring of Ewing sarcoma in children and adolescents

• Main Authors: Markus G. Seidel (Author), Karl Kashofer (Author), Tina Moser (Author), Andrea Thueringer (Author), Bernadette Liegl-Atzwanger (Author), Andreas Leithner (Author), Joanna Szkandera (Author), Martin Benesch (Author), Amin El-Heliebi (Author), Ellen Heitzer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundTreatment stratification and response assessment in pediatric sarcomas has relied on imaging studies and surgical/histopathological evidence of vital tumor cells. Such studies and evidence collection processes often involve radiation and/or general anesthesia in children. Cell-free circula...