Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation

• Main Authors: Murumalla Ravi (Author), Bencharif Karima (Author), Gence Lydie (Author), Bhattacharya Amritendu (Author), Tallet Frank (Author), Gonthier Marie-Paule (Author), Petrosino Stefania (Author), di Marzo Vincenzo (Author), Cesari Maya (Author), Hoareau Laurence (Author), Roche Régis (Author)
• Format: Book
• Published: BMC, 2011-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Obesity is characterized by inflammation, caused by increase in proinflammatory cytokines, a key factor for the development of insulin resistance. SR141716A, a cannabinoid receptor 1 (CB1) antagonist, shows significant improvement in...