PET Imaging of Neurofibromatosis Type 1 with a Fluorine-18 Labeled Tryptophan Radiotracer

• Main Authors: Xuyi Yue (Author), Erik Stauff (Author), Shriya Boyapati (Author), Sigrid A. Langhans (Author), Wenqi Xu (Author), Sokratis Makrogiannis (Author), Uchenna J. Okorie (Author), Azubuike M. Okorie (Author), Vinay V. R. Kandula (Author), Heidi H. Kecskemethy (Author), Rahul M. Nikam (Author), Lauren W. Averill (Author), Thomas H. Shaffer (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder. Plexiform neurofibromas (PNFs) are benign tumors commonly formed in patients with NF1. PNFs have a high incidence of developing into malignant peripheral nerve sheath tumors (MPNSTs) with a 5-year survival rate of only 30%. Therefore, the...