Derivation of Pluripotent Cells from Mouse SSCs Seems to Be Age Dependent

• Main Authors: Hossein Azizi (Author), Sabine Conrad (Author), Ursula Hinz (Author), Behrouz Asgari (Author), Daniel Nanus (Author), Heike Peterziel (Author), Akbar Hajizadeh Moghaddam (Author), Hossein Baharvand (Author), Thomas Skutella (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we aimed to answer important and fundamental questions in germ cell biology with special focus on the age of the male donor cells and the possibility to generate embryonic stem cell- (ESC-) like cells. While it is believed that spermatogonial stem cells (SSCs) and truly pluripotent ESC-like ce...