The Curcumin Derivative, H10, Suppresses Hormone-Dependent Prostate Cancer by Inhibiting 17β-Hydroxysteroid Dehydrogenase Type 3

• Asıl Yazarlar: Yating Cheng (Yazar), Yan Yang (Yazar), Yinan Wu (Yazar), Wencheng Wang (Yazar), Lichun Xiao (Yazar), Yifan Zhang (Yazar), Jianzhong Tang (Yazar), Ya-Dong Huang (Yazar), Shu Zhang (Yazar), Qi Xiang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) enzyme is a potential therapeutic target for hormone-dependent prostate cancer, as it is the key enzyme in the last step of testosterone (T) biosynthesis. A curcumin analog, H10, was optimized for inhibiting T production in LC540 cells that stab...