Pharmacokinetic/Pharmacodynamic Adequacy of Novel β-Lactam/β-Lactamase Inhibitors against Gram-Negative Bacterial in Critically Ill Patients

Pharmacokinetic/Pharmacodynamic Adequacy of Novel β-Lactam/β-Lactamase Inhibitors against Gram-Negative Bacterial in Critically Ill Patients

The optimal regimens of novel β-lactam/β-lactamase inhibitors (BLBLIs), ceftazidime/avibactam, ceftolozane/tazobactam, and meropenem/vaborbactam, are not well defined in critically ill patients. This study was conducted to identify optimal regimens of BLBLIs in these patients. A Monte Carlo simulati...

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Main Authors: Ruiying Han (Author), Dan Sun (Author), Sihan Li (Author), Jiaojiao Chen (Author), Mengmeng Teng (Author), Bo Yang (Author), Yalin Dong (Author), Taotao Wang (Author)
Format: Book
Published: MDPI AG, 2021-08-01T00:00:00Z.
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