Folic acid-modified reverse micelle-lipid nanocapsules overcome intestinal barriers and improve the oral delivery of peptides

• Main Authors: Jibiao He (Author), Ruihuan Ding (Author), Yuping Tao (Author), Zhenyu Zhao (Author), Ranran Yuan (Author), Houqian Zhang (Author), Aiping Wang (Author), Kaoxiang Sun (Author), Youxin Li (Author), Yanan Shi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractThe oral absorption of exenatide, a type 2 diabetes medication, can be increased by employing lipid nanocapsules (LNC). To increase mucus permeability and exenatide intestinal absorption, reverse micelle lipid nanocapsules (RM-LNC) were prepared and their surface was modified with DSPE-PEG-F...