Indigofera suffruticosa aerial parts extract induce G2/M arrest and ATR/CHK1 pathway in Jurkat cells

• Main Authors: Hong-Loan Tran (Author), Kuei-Hung Lai (Author), Hsun-Shuo Chang (Author), Yi-Siao Chen (Author), Hui-Chun Wang (Author), Shuen-Shin Yang (Author), Hsueh-Wei Chang (Author), Chin-Mu Hsu (Author), Chia-Hung Yen (Author), Hui-Hua Hsiao (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Indigofera suffruticosa Mill. is used as a folk medicine for treating patients with leukemia, however very little is known regarding the molecular mechanism of its anti-leukemic activity and the chemical profile of the active extract. The present study aimed to reveal the molecul...