Design, development and evaluation of rK28-based point-of-care tests for improving rapid diagnosis of visceral leishmaniasis.

• Main Authors: Sowmya Pattabhi (Author), Jacqueline Whittle (Author), Raodoh Mohamath (Author), Sayda El-Safi (Author), Garner G Moulton (Author), Jeffrey A Guderian (Author), Danny Colombara (Author), Asem O Abdoon (Author), Maowia M Mukhtar (Author), Dinesh Mondal (Author), Javan Esfandiari (Author), Shailendra Kumar (Author), Peter Chun (Author), Steven G Reed (Author), Ajay Bhatia (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Visceral leishmaniasis (VL) is diagnosed by microscopic confirmation of the parasite in bone marrow, spleen or lymph node aspirates. These procedures are unsuitable for rapid diagnosis of VL in field settings. The development of rK39-based rapid diagnostic tests (RDT) revolutionized diag...