Stability Indicating HPLC-ECD Method for the Analysis of Clarithromycin in Pharmaceutical Dosage Forms: Method Scaling versus Re-Validation

• Glavni autori: Pedzisai A. Makoni (Autor), Mellisa T.R. Chikukwa (Autor), Sandile M.M. Khamanga (Autor), Roderick B. Walker (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2019-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD). The method was validated using International Conferenc...