Differential Cellular and Molecular Effects of Butyrate and Trichostatin A on Vascular Smooth Muscle Cells

The histone deacetylase (HDAC) inhibitors, butyrate and trichostatin A (TSA), are epigenetic histone modifiers and proliferation inhibitors by downregulating cyclin D1, a positive cell cycle regulator, and upregulating p21Cip1 and INK family of proteins, negative cell cycle regulators. Our recent st...

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Main Authors: Kasturi Ranganna (Author), Frank M. Yatsu (Author), Omana P. Mathew (Author), Shirlette G. Milton (Author)
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出版: MDPI AG, 2012-09-01T00:00:00Z.
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