Differential Cellular and Molecular Effects of Butyrate and Trichostatin A on Vascular Smooth Muscle Cells
The histone deacetylase (HDAC) inhibitors, butyrate and trichostatin A (TSA), are epigenetic histone modifiers and proliferation inhibitors by downregulating cyclin D1, a positive cell cycle regulator, and upregulating p21Cip1 and INK family of proteins, negative cell cycle regulators. Our recent st...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2012-09-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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