BRAF mutation in hairy cell leukemia
BRAF is a serine/threonine kinase with a regulatory role in the mitogen-activated protein kinase (MAPK) signaling pathway. A mutation in the RAF gene, especially in BRAF protein, leads to an increased stimulation of this cascade, causing uncontrolled cell division and development of malignancy. Seve...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2014-09-01T00:00:00Z.
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