ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK

• Главные авторы: Peiran Song (Автор), Gang Bai (Автор), Shingpan Chan (Автор), Tao Zhang (Автор), Linjiang Tong (Автор), Yi Su (Автор), Yanyan Shen (Автор), Yi Chen (Автор), Yingqiang Liu (Автор), Mengzhen Lai (Автор), Yi Ning (Автор), Haotian Tang (Автор), Yan Fang (Автор), Ke Ding (Автор), Jian Ding (Автор), Hua Xie (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Hyperactivation of Bruton's tyrosine kinase (BTK) or interleukin-2-inducible T cell kinase (ITK) has been attributed to the pathogenesis of B-cell lymphoma or T-cell leukemia, respectively, which suggests that Bruton's tyrosine kinase and interleukin-2-inducible T cell kinase are critical...