Obesity-Induced Methylation of Osteopontin Contributes to Adipogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells

• Main Authors: Min Tang (Author), Rui Chen (Author), Hao Wang (Author), Guowei Sun (Author), Fan Yin (Author), Beibei Liang (Author), Yang Yang (Author), Gaowa Sharen (Author), Huafeng Wei (Author), Xuyu Zhou (Author), Gang Huang (Author), Jian Zhao (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is a major risk factor for many chronic diseases, including diabetes, fatty livers, and cancer. Expansion of the adipose mass has been shown to be related to adipogenic differentiation of adipose-derived mesenchymal stem cells (ASCs). However, the underlying mechanism of this effect has yet...