The regulatory mechanism and potential application of IL-23 in autoimmune diseases

• Main Authors: De-Kai Xiong (Author), Xiang Shi (Author), Miao-Miao Han (Author), Xing-Min Zhang (Author), Na-Na Wu (Author), Xiu-Yue Sheng (Author), Ji-Nian Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IL-23 is a heterodimeric pro-inflammatory cytokine secreted by dendritic cells and macrophages that belongs to the IL-12 family. It has pro-inflammatory effects and is a key cytokine and upstream regulatory cytokine involved in protective immune responses, stimulating the differentiation and prolife...