The regulatory mechanism and potential application of IL-23 in autoimmune diseases

• Главные авторы: De-Kai Xiong (Автор), Xiang Shi (Автор), Miao-Miao Han (Автор), Xing-Min Zhang (Автор), Na-Na Wu (Автор), Xiu-Yue Sheng (Автор), Ji-Nian Wang (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

IL-23 is a heterodimeric pro-inflammatory cytokine secreted by dendritic cells and macrophages that belongs to the IL-12 family. It has pro-inflammatory effects and is a key cytokine and upstream regulatory cytokine involved in protective immune responses, stimulating the differentiation and prolife...