Management and prediction of immune-related adverse events for PD1/PDL-1 immunotherapy in colorectal cancer

• Main Authors: Liting Sun (Author), Cong Meng (Author), Xiao Zhang (Author), Jiale Gao (Author), Pengyu Wei (Author), Jie Zhang (Author), Zhongtao Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Programmed cell death protein (PD-1) is an important immunosuppressive molecule, which can inhibit interaction between PD-1 and its ligand PD-L1, further enhancing the T cell response and anti-tumor activity, which is called immune checkpoint blockade. Immunotherapy, represented by immune checkpoint...