Pharmacogenetic Aspects of the Interaction of AT1 Receptor Antagonists With ATP-Binding Cassette Transporter ABCG2

• Asıl Yazarlar: Anne Ripperger (Yazar), Anna Krischer (Yazar), Dina Robaa (Yazar), Wolfgang Sippl (Yazar), Ralf A. Benndorf (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The ATP-binding cassette transporter ABCG2 (BCRP and MXR) is involved in the absorption, distribution, and elimination of numerous drugs. Thus, drugs that are able to reduce the activity of ABCG2, e.g., antihypertensive AT1 receptor antagonists (ARBs), may cause drug-drug interactions and compromise...