Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma

• Main Authors: Germano Aguiar Ferreira (Author), Carolina Hassibe Thomé (Author), Clarice Izumi (Author), Mariana Lopes Grassi (Author), Guilherme Pauperio Lanfredi (Author), Marcus Smolka (Author), Vitor Marcel Faça (Author), Francisco José Candido dos Reis (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression. Exosomes, extracellular vesicles containing proteins involved in cell-cell communication, have emerged as a potential source of biomarkers for sever...