Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes

• Hoofdauteurs: Rojanasakul Yon (Auteur), Yun Chawon (Auteur), Kramer Sara J (Auteur), Dorfleutner Andrea (Auteur), Bryan Nicole B (Auteur), Stehlik Christian (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2010-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The apoptotic speck-like protein containing a caspase recruitment domain (ASC) is the essential adaptor protein for caspase 1 mediated interleukin (IL)-1β and IL-18 processing in inflammasomes. It bridges activated Nod like receptors...