An in vitro human mammary epithelial cell permeability assay to assess drug secretion into breast milk

• Main Authors: Tao Zhang (Author), Zachary Applebee (Author), Peng Zou (Author), Zhen Wang (Author), Erika Solano Diaz (Author), Yanyan Li (Author)
• 格式: 图书
• 出版: Elsevier, 2022-12-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Determining the amount of a drug transferred into breast milk is critical for benefit-risk analysis of breastfeeding when a lactating mother takes medications. In this study, we developed a human mammary epithelial cell (MEC)-based permeability assay to assess drug permeability across the mammary ep...