Dehydroepiandrosterone Sulfate Reduces Acoustic Injury of the Guinea-Pig Cochlea

• Main Authors: Keiji Tabuchi (Author), Hidekazu Murashita (Author), Tadamichi Tobita (Author), Keiko Oikawa (Author), Shigeki Tsuji (Author), Isao Uemaetomari (Author), Akira Hara (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study was performed to determine effects of dehydroepiandrosterone sulfate (DHEAS), a neurosteroid, on acoustic injury. Albino guinea pigs were exposed to a 2 kHz pure tone of 120 or 125 dB sound pressure level for 10 min immediately after intravenous administration of DHEAS. Statistical...