A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis

• Main Authors: Michael E. Yarrington (Author), Rebekah W. Moehring (Author), Michael Z. David (Author), Keith W. Hamilton (Author), Michael Klompas (Author), Chanu Rhee (Author), Kevin Hsueh (Author), Elizabeth Dodds Ashley (Author), Ronda L. Sinkowitz-Cochran (Author), Matthew Ryan (Author), Deverick J. Anderson (Author), for the DETOURS Expert Panel of the CDC Prevention Epicenters Program (Author)
• Format: Book
• Published: Cambridge University Press, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background: Early administration of antibiotics in sepsis is associated with improved patient outcomes, but safe and generalizable approaches to de-escalate or discontinue antibiotics after suspected sepsis events are unknown. Methods: We used a modified Delphi approach to identify safety c...