Concomitant telomere attrition is associated with spinal muscular atrophy in highly inbred region of North India: unraveling the thread in Kashmir region

• Main Authors: Rukhsana Hassan (Author), Gh Rasool Bhat (Author), Feroze Ahmad Mir (Author), Hilal Ahmad Ganie (Author), Ifra Mushtaq (Author), Mushtaq Ahmad Bhat (Author), Ravouf Parvez Asimi (Author), Dil Afroze (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Spinal muscular atrophy (SMA) is a rare genetic disorder that unequivocally results in the degeneration of motor neurons, leading to muscle weakness and atrophy. This condition is caused by a mutation in the survival motor neuron 1 (SMN1) gene, which inevitably results in a deficiency of th...