Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain

• Main Authors: Xingguang Luo (Author), Xiandong Lin (Author), Jaime S. Ide (Author), Xinqun Luo (Author), Yong Zhang (Author), Jianying Xu (Author), Leilei Wang (Author), Yu Chen (Author), Wenhong Cheng (Author), Jianming Zheng (Author), Zhiren Wang (Author), Ting Yu (Author), Reyisha Taximaimaiti (Author), Xiaozhong Jing (Author), Xiaoping Wang (Author), Yuping Cao (Author), Yunlong Tan (Author), Chiang-Shan R. Li (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Attention deficit hyperactivity disorder (ADHD) is associated with reduction of cortical and subcortical gray matter volumes (GMVs). The kinectin 1 gene (KTN1) has recently been reported to significantly regulate GMVs and ADHD risk. In this study, we aimed to identify sex-specific, replicab...