A small bioactive glycoside inhibits epsilon toxin and prevents cell death

• Main Authors: Abhishek Shivappagowdar (Author), Soumya Pati (Author), Chintam Narayana (Author), Rajagopal Ayana (Author), Himani Kaushik (Author), Raj Sah (Author), Swati Garg (Author), Ashish Khanna (Author), Jyoti Kumari (Author), Lalit Garg (Author), Ram Sagar (Author), Shailja Singh (Author)
• Format: Book
• Published: The Company of Biologists, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clostridium perfringens epsilon toxin (Etx) is categorized as the third most lethal bioterrorism agent by the Centers for Disease Control and Prevention (CDC), with no therapeutic counter measures available for humans. Here, we have developed a high-affinity inhibitory compound by synthesizing and e...