A novel live-attenuated vaccine candidate for mayaro Fever.

• Main Authors: William J Weise (Author), Meghan E Hermance (Author), Naomi Forrester (Author), A Paige Adams (Author), Rose Langsjoen (Author), Rodion Gorchakov (Author), Eryu Wang (Author), Maria D H Alcorn (Author), Konstantin Tsetsarkin (Author), Scott C Weaver (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mayaro virus (MAYV) is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we capitalized on an IRES-based approach to develop a l...