Risk variants in <it>BMP4 </it>promoters for nonsyndromic cleft lip/palate in a Chilean population

• Main Authors: Suazo José (Author), Tapia Julio C (Author), Santos José Luis (Author), Castro Víctor G (Author), Colombo Alicia (Author), Blanco Rafael (Author)
• Format: Book
• Published: BMC, 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Bone morphogenetic protein 4 gene (<it>BMP4</it>) plays a key role during maxillofacial development, since orofacial clefts are observed in animals when this gene is conditionally inactivated. We recently reported the exi...