Single cell spatial profiling of FFPE splenic tissue from a humanized mouse model of HIV infection

• Главные авторы: Guoxin Wu (Автор), Samuel H. Keller (Автор), Luca Sardo (Автор), Brian Magliaro (Автор), Paul Zuck (Автор), Carl J. Balibar (Автор), Claire Williams (Автор), Liuliu Pan (Автор), Mark Gregory (Автор), Kathy Ton (Автор), Jill Maxwell (Автор), Carol Cheney (Автор), Tom Rush (Автор), Bonnie J. Howell (Автор)
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• Опубликовано: BMC, 2024-10-01T00:00:00Z.
• Предметы: article
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Abstract Background Latency remains a major obstacle to finding a cure for HIV despite the availability of antiretroviral therapy. Due to virus dormancy, limited biomarkers are available to identify latent HIV-infected cells. Profiling of individual HIV-infected cells is needed to explore potential...