The influence of telmisartan on metformin pharmacokinetics and pharmacodynamics

• Main Authors: Jiagen Wen (Author), Meizi Zeng (Author), Zhaoqian Liu (Author), Honghao Zhou (Author), Heng Xu (Author), Min Huang (Author), Wei Zhang (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin is the most widely used drug among type 2 diabetes mellitus patients. However, drug interaction on metformin will influence its glucose-lowering effect or increase its side effect of lactic acidosis. In this study, a randomized, two-stage, crossover study was conducted to unveil the potent...