Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis

• Үндсэн зохиолчид: Bernardo Blanco-Sánchez (Зохиогч), Aurélie Clément (Зохиогч), Javier Fierro (Зохиогч), Philip Washbourne (Зохиогч), Monte Westerfield (Зохиогч)
• Формат: Ном
• Хэвлэсэн: The Company of Biologists, 2014-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural deafness and progressive retinal degeneration. Mutations in several different genes produce USH, but the proximal cause of sensory cell death remains mysterious. We adapted a pro...