Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration

• المؤلفون الرئيسيون: Pasquale Cocchiaro (مؤلف), Vincenzo Di Donato (مؤلف), Davide Rubbini (مؤلف), Rodolfo Mastropasqua (مؤلف), Marcello Allegretti (مؤلف), Flavio Mantelli (مؤلف), Andrea Aramini (مؤلف), Laura Brandolini (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Nerve growth factor (NGF) is the best characterized neurotrophin, and it is known to play an important role in ocular homeostasis. Here, we demonstrated the expression of NGF receptors in adult zebrafish retina and optimized a light-induced retina degeneration (LID) zebrafish model that mimics human...