The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer's Disease

• Main Authors: Filippo S. Giorgi (Author), Larisa Ryskalin (Author), Riccardo Ruffoli (Author), Francesca Biagioni (Author), Fiona Limanaqi (Author), Michela Ferrucci (Author), Carla L. Busceti (Author), Ubaldo Bonuccelli (Author), Francesco Fornai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's Disease (AD) features the accumulation of β-amyloid and Tau aggregates, which deposit as extracellular plaques and intracellular neurofibrillary tangles (NFTs), respectively. Neuronal Tau aggregates may appear early in life, in the absence of clinical symptoms. This occurs in the br...