The human batokine EPDR1 regulates β-cell metabolism and function

• Main Authors: Luis Rodrigo Cataldo (Author), Qian Gao (Author), Lidia Argemi-Muntadas (Author), Ondrej Hodek (Author), Elaine Cowan (Author), Sergey Hladkou (Author), Sevda Gheibi (Author), Peter Spégel (Author), Rashmi B. Prasad (Author), Lena Eliasson (Author), Camilla Scheele (Author), Malin Fex (Author), Hindrik Mulder (Author), Thomas Moritz (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Ependymin-Related Protein 1 (EPDR1) was recently identified as a secreted human batokine regulating mitochondrial respiration linked to thermogenesis in brown fat. Despite that EPDR1 is expressed in human pancreatic β-cells and that glucose-stimulated mitochondrial metabolism is critical...