Nano-Silica Carriers Coated by Chloramphenicol: Synthesis, Characterization, and Grinding Trial as a Way to Improve the Release Profile

• Príomhchruthaitheoirí: Radosław Balwierz (Údar), Dawid Bursy (Údar), Paweł Biernat (Údar), Nataliia Hudz (Údar), Mariia Shanaida (Údar), Łukasz Krzemiński (Údar), Paweł Skóra (Údar), Monika Biernat (Údar), Wioletta Ochędzan Siodłak (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2022-06-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Silica nanoparticles were applied as the carrier of chloramphenicol (2,2-dichloro-<i>N</i>-[(1<i>R</i>,2<i>R</i>)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide), and were loaded in a 1% carbopol-based gel (poly(acrylic acid)), which allowed obtainment of an...