Developability considerations for bispecific and multispecific antibodies

• Autores principales: Alaa Amash (Autor), Gesa Volkers (Autor), Patrick Farber (Autor), Daniel Griffin (Autor), K. Shawn Davison (Autor), Allison Goodman (Autor), Raffi Tonikian (Autor), Aaron Yamniuk (Autor), Bryan Barnhart (Autor), Tim Jacobs (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Bispecific antibodies (bsAb) and multispecific antibodies (msAb) encompass a diverse variety of formats that can concurrently bind multiple epitopes, unlocking mechanisms to address previously difficult-to-treat or incurable diseases. Early assessment of candidate developability enables demotion of...